AlloMAPS

Allosteric Mutation Analysis and Polymorphism of Signaling database


The database provides data on the energetics of communication in proteins with well-documented allosteric regulation,
allosteric signalling in PDBselect chains, and allosteric effects of mutations.

Update (18 Aug 2021): Added trRosetta-modelled structures of Pfam protein domains, including allosteric probing maps (see Tutorial).

Allosteric proteins

Allosteric proteins

Signalling in proteins with well-documented allosteric regulation

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PDBselect CATH

PDBselect chains

Allosteric signaling maps (ASMs) in CATH-annotated PDBselect chains

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Allosteric polymorphism

Allosteric polymorphism

Documented pathological SNPs and predicted polymorphism

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AlloMAPS_Pfam 6370

AlloMAPS_Pfam 6370

trRosetta-predicted structures of Pfam domains

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